Gene information
Official symbol SERPINA3
Official full name serpin family A member 3
Gene type protein-coding gene
Chromosome14q32.13
Alias symbolACT
Previous symbolAACT
Gene familySerpin peptidase inhibitors
Resources
Entrez Gene 12
HGNC HGNC:16
Ensembl ENSG00000196136
Vega OTTHUMG00000029851
UCSC uc001yds.4
GO terms: 26 records
GO Description Category LogP Number of genes Detail
GO:0002526 acute inflammatory response GO Biological Processes -34.5980034 29 More
GO:0004857 enzyme inhibitor activity GO Molecular Functions -18.4005452 35 More
GO:0004866 endopeptidase inhibitor activity GO Molecular Functions -20.0646267 27 More
GO:0004867 serine-type endopeptidase inhibitor activity GO Molecular Functions -8.20238048 12 More
GO:0006953 acute-phase response GO Biological Processes -24.9631834 19 More
GO:0006954 inflammatory response GO Biological Processes -86.5569367 100 More
GO:0010466 negative regulation of peptidase activity GO Biological Processes -24.1438543 35 More
GO:0010951 negative regulation of endopeptidase activity GO Biological Processes -24.7873219 35 More
GO:0030162 regulation of proteolysis GO Biological Processes -41.2267045 73 More
GO:0030312 external encapsulating structure GO Cellular Components -73.3689453 93 More
GO:0030414 peptidase inhibitor activity GO Molecular Functions -19.6181890 27 More
GO:0031012 extracellular matrix GO Cellular Components -73.4416071 93 More
GO:0031091 platelet alpha granule GO Cellular Components -43.3287145 36 More
GO:0031093 platelet alpha granule lumen GO Cellular Components -40.0105787 31 More
GO:0031983 vesicle lumen GO Cellular Components -60.5757669 68 More
GO:0034774 secretory granule lumen GO Cellular Components -58.3093741 66 More
GO:0043086 negative regulation of catalytic activity GO Biological Processes -41.1437610 130 More
GO:0045861 negative regulation of proteolysis GO Biological Processes -27.9905009 43 More
GO:0051346 negative regulation of hydrolase activity GO Biological Processes -26.0030636 42 More
GO:0052547 regulation of peptidase activity GO Biological Processes -35.5643317 55 More
GO:0052548 regulation of endopeptidase activity GO Biological Processes -34.9486589 53 More
GO:0060205 cytoplasmic vesicle lumen GO Cellular Components -59.3932782 67 More
GO:0061134 peptidase regulator activity GO Molecular Functions -19.3582235 29 More
GO:0061135 endopeptidase regulator activity GO Molecular Functions -19.1908633 27 More
GO:0062023 collagen-containing extracellular matrix GO Cellular Components -67.6170082 80 More
GO:0072562 blood microparticle GO Cellular Components -39.0217600 39 More
Related studies: 3 records
Molecular factor Omics type Application Objective MI type Reference
alpha-1-antichymotrypsin proteomics heart failure[prognosis (bad)] acute myocardial infarction Kazmierczak M et al. Int J Cardiol. 1995
alpha-1-antichymotrypsin proteomics acute myocardial infarction[diagnosis] acute myocardial infarction Zhao L et al. Int J Cardiol. 2019
alpha-1-antichymotrypsin proteomics major adverse cardiovascular events[prognosis (bad)] acute myocardial infarction Zhao L et al. Int J Cardiol. 2019
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